Tripartite motif containing 28
WebMar 10, 2024 · Description Members of the tripartite motif (TRIM) protein family, such as TRIM32, contain RING, BBOX, and coiled-coil domains, as well as variable C-terminal domains. TRIM32 functions as an E3 ubiquitin ligase in the ubiquitin-proteasome system, which is responsible for protein degradation (summary by Locke et al., 2009 ). WebApr 12, 2024 · Tripartite motif containing 28 (TRIM28), also called TIF1β or KAP1, is a member of the TIF1 family proteins with a PHD domain and a bromo domain in the C …
Tripartite motif containing 28
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WebMar 21, 2024 · TRIM17 (Tripartite Motif Containing 17) is a Protein Coding gene. Diseases associated with TRIM17 include Mulibrey Nanism and Opitz-Kaveggia Syndrome . Among its related pathways are Interferon gamma signaling and Cytokine Signaling in Immune system . WebSep 13, 2024 · The tripartite motif (TRIM) protein family is a highly conserved group of E3 ligases with 77 members known in the human, most of which consist of a RING-finger domain, one or two B-box domains, and a coiled-coil domain. Generally, TRIM proteins function as E3 ligases to facilitate specific proteasomal degradation of target proteins.
WebHuman E3 Ubiquitin Ligases. These ligases can be sorted alphabetically by Gene Symbol, Protein Name, or Class by clicking on the respective header. This information was culled primarily from several existing resources (click to open): Cell Signaling , Inc., hUbiqutome database , Qiagen Ubiquitin Ligases PCR Array , UbiProt Database , DUDE v. 1. ... WebThese proteins are defined by the presence of a tripartite motif composed of three zinc-binding domains, a RING finger, one or two B-box motifs, a coiled-coil region and a highly …
WebJan 23, 2024 · Tripartite motif-containing 28 (TRIM28) is an E3 ubiquitin ligase belonging to tripartite motif (TRIM) family. TRIM28 not only binds and degrades its downstream target, … Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene.
WebTrim28 tripartite motif-containing 28 [ (Norway rat)] Gene ID: 116698, updated on 8-Dec-2024 Summary Predicted to enable several functions, including promoter-specific chromatin binding activity; protein domain specific binding activity; and ubiquitin-like protein transferase activity.
WebApr 4, 2024 · Trim28 tripartite motif-containing 28 [ (house mouse)] Gene ID: 21849, updated on 14-Feb-2024. Summary. Enables DNA binding activity; protein kinase activity; and … luthier thickness sanderWebAug 1, 2024 · A decreased or increased capacity of PQC is associated with various diseases, e.g., neurodegenerative diseases and cancers. Recently, increasing evidences have suggested that tripartite... luthier thonon les bainsWebMar 21, 2024 · TRIM28 tripartite motif containing 28 Gene ID: 10155, updated on 5-Feb-2024 Gene type: protein coding Also known as: KAP1; TF1B; RNF96; TIF1B; PPP1R157; TIF1beta See all available tests in GTR for this gene Go to complete Gene record for TRIM28 Go to Variation Viewer for TRIM28 variants Summary jd sports at fosse parkWebNov 1, 2011 · As reported in this article, we have identified the tripartite motif-containing protein 28 (TRIM28) as a binding partner of IRF7. We have demonstrated that TRIM28 … luthier timber australiaWebAug 25, 2024 · Protein quality control (PQC) is pivotal for eukaryotic cells to eliminate misfolded proteins and maintain cellular homeostasis. A decreased or increased capacity of PQC is associated with various diseases, e.g., neurodegenerative diseases and cancers. Recently, increasing evidences have suggested that tripartite motif-containing family … jd sports back supportWebNov 28, 2013 · In previous mass spectrometry and coimmune precipitation studies, we identified tripartite motif-containing 28 (TRIM28; also known as transcriptional intermediary factor1β and Krüppel-associated box-associated protein-1) as a cofactor that specifically copurified with an NR2C1/NR2C2 (TR2/TR4) orphan nuclear receptor heterodimer that … jd sports at bluewaterWebOct 18, 2015 · Tripartite motif (TRIM) proteins are involved in tumorigenesis. Here, we examined the expression, biological function, and clinical significance of tripartite motif containing 28 (TRIM28) in glioma, a locally aggressive brain tumor. First, TRIM28 expression was significantly higher in glioma (n = 138) than in non-glioma controls (n = 6). luthier thickness gauge